An Orthotopic Model for Human Uveal Melanoma in SCID Mice
β Scribed by Arthur J. Mueller; Andrew J. Maniotis; William R. Freeman; Dirk-Uwe Bartsch; Ulrich C. Schaller; Germaine Bergeron-Lynn; Lingyun Cheng; Ibrahim Taskintuna; Xue Chen; June Kan-Mitchell; Robert Folberg
- Book ID
- 115641272
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 217 KB
- Volume
- 64
- Category
- Article
- ISSN
- 0026-2862
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## Abstract We have shown that administration of a novel antiβCD54 monoclonal antibody (UV3) results in longβterm survival of SCID mice bearing human myeloma xenografts. Previous studies have demonstrated a link between the expression of CD54 and the progression of uveal melanoma. Our study assesse
The term humanized mouse in this text refers to a mouse in which human tissues and cells have been transplanted and show the same biological function as they do in the human body. That is, the physiological properties and functions of tra- planted human tissues and cells can be analyzed in the mouse