An Optical Approach for Drug Screening Based on Light-Harvesting Conjugated Polyelectrolytes

✍ Scribed by Lingling An; Libing Liu; Shu Wang; Guillermo C. Bazan

• Book ID: 102728277
• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: English
• Weight: 650 KB
• Volume: 48
• Category: Article
• ISSN: 0044-8249
• DOI: 10.1002/anie.200900758

✦ Synopsis

Abstract

Drugs turn the light off: Conjugated polyelectrolytes (CPEs) have been used in fluorescent assays for real‐time screening of small molecules that prevent the RNA–protein complexation that is important for virus replication and thereby can be considered potential initial candidates for drug discovery (see picture).magnified image