Objective The main aim of this study was to explore the efficacy and safety of duloxetine, a serotonin and norepinephrine reuptake inhibitor, in the treatment of adolescents with attention deficit/hyperactivity disorder (ADHD). Methods Seventeen adolescents aged 11-18 years, diagnosed with ADHD, par
An open trial of buspirone in the treatment of attention-deficit disorder
β Scribed by Helmut Niederhofer
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 48 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0885-6222
- DOI
- 10.1002/hup.511
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Objective
Medications such as clonidine have been shown to facilitate calming, to enhance frustration tolerance, and to reduce aggression in attention deficit disorder (ADD) patients. The use of buspirone was studied as an alternative because of its longer excretion halfβlife, decreased sedative side effects and more selective binding profile.
Method
Eight psychiatric outpatients diagnosed with ADD were rated at baseline and while taking buspirone to determine its efficacy as a treatment for ADD. Comparisons of WenderβUtah ratings within subject were used to measure behavioural changes in the subjects.
Results
During buspirone treatment, the patients' mean scores improved significantly overall and in hyperactivity, inattention and immaturity factors.
Conclusions
This preliminary study indicates that buspirone might be a beneficial and useful treatment of ADD, reducing hyperactive behaviours and enabling greater attentional ability with minimal side effects. Copyright Β© 2003 John Wiley & Sons, Ltd.
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