An open-label, phase 2 trial of denosumab in the treatment of relapsed or plateau-phase multiple myeloma
β Scribed by Ravi Vij; Noemi Horvath; Andrew Spencer; Kerry Taylor; Saroj Vadhan-Raj; Robert Vescio; Judy Smith; Yi Qian; Howard Yeh; Susie Jun
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 187 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0361-8609
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π SIMILAR VOLUMES
## BACKGROUND. Interferon (IFN) has demonstrated activity in the treatment of patients with multiple myeloma. A previous Eastern Cooperative Oncology Group (ECOG) study suggested that the rates of complete response (CR) and survival were increased with a regimen that alternated IFN with chemothera
The bone marrow plasma cell labeling index (PCLI) as measured by bromodeoxyuridine uptake is a well-established independent prognostic factor for patients with newly diagnosed multiple myeloma, but the test is not easily done in most laboratories. The purpose of this study was to determine if the pr