✦ LIBER ✦

An Ontology for Pharmaceutical Ligands and Its Application for in Silico Screening and Library Design.

✍ Scribed by Ansgar Schuffenhauer; Juerg Zimmermann; Ruedi Stoop; Jan-Jan van der Vyver; Steffano Lecchini; Edgar Jacoby

Publisher: John Wiley and Sons
Year: 2010
Weight: 24 KB
Volume: 33
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200242245

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

An Efficient in Silico Screening Method

An Efficient in Silico Screening Method Based on the Protein—Compound Affinity Matrix and Its Application to the Design of a Focused Library for Cytochrome P450 (CYP) Ligands.

✍ Yoshifumi Fukunishi; Shinichi Hojo; Haruki Nakamura 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 11 KB 👁 2 views

Pharmacophore Identification, in Silico

Pharmacophore Identification, in Silico Screening, and Virtual Library Design for Inhibitors of the Human Factor Xa.

✍ Eva M. Krovat; Karin H. Fruehwirth; Thierry Langer 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 8 KB 👁 2 views

Mass spectrometry for enzyme assays and

Mass spectrometry for enzyme assays and inhibitor screening: An emerging application in pharmaceutical research

✍ Kenneth D. Greis 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 628 KB

## Abstract Robust methods that monitor enzyme activity and inhibitor potency are crucial to drug discovery and development. Over the past 20 years, mass spectrometric methods have increasingly been used to measure enzyme activity and kinetics. However, for rapid screening of inhibitory compounds,

Small-Molecule Affinity Ligands for Prot

Small-Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In-line Screening of an Optically Encoded Library

✍ Jakob E. Rasmussen; Christine B. Schiødt; Søren F. Christensen; Leif Nørskov-Lau 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 610 KB

Small-Molecule Affinity Ligands for Prot

Small-Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In-line Screening of an Optically Encoded Library

✍ Jakob E. Rasmussen; Christine B. Schiødt; Søren F. Christensen; Leif Nørskov-Lau 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 630 KB

An algorithm for finding the extreme val

An algorithm for finding the extreme values of a function of many variables and its application in the automatic design of astronomical optical systems

✍ Ding-qian Su; Ya-nan Wang; Bi-fang Zhou; Sheng-dong Lu 📂 Article 📅 1980 🏛 Elsevier Science ⚖ 260 KB