## Abstract Two technical hurdles, gene delivery and target specificity, have hindered the development of effective cancer gene therapies. In order to circumvent the problem of tumor specificity, the suicide gene, HSVโ1 thymidine kinase (HSVโTk), was modified with a complex 5โฒ upstreamโuntranslated
โฆ LIBER โฆ
An oncolytic adenovirus expressing herpes simplex virus-thymidine kinase for targeting cancer therapy: Anin vitroevaluation
โ Scribed by Fei-qun Zheng; Yin Xu; Yi-de Qin; Ren-jie Yang; Jun Han
- Book ID
- 107466961
- Publisher
- Chinese Anti-Cancer Association
- Year
- 2009
- Tongue
- English
- Weight
- 617 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1000-9604
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Cancer-specific targeting of an adenovir
โ
J. Michael Mathis; B. Jill Williams; Don A. Sibley; Jennifer L. Carroll; Jie Li;
๐
Article
๐
2006
๐
John Wiley and Sons
๐
English
โ 533 KB
Production and characterization of a bic
โ
Pizzato, M; Franchin, E; Calvi, P; Boschetto, R; Colombo, M; Ferrini, S; Palรน, G
๐
Article
๐
1998
๐
Nature Publishing Group
๐
English
โ 84 KB
Adenovirus-mediated herpes simplex virus
โ
Simon J. Hall; Steven E. Mutchnik; Shu-Hsia Chen; Savio L.C. Woo; Timothy C. Tho
๐
Article
๐
1997
๐
John Wiley and Sons
๐
French
โ 106 KB
๐ 2 views
It is critical to develop new therapies, such as gene therapy, which can impact on both local and metastatic prostate cancer progression. We have developed an orthotopic mouse model of metastatic prostate cancer using a cell line (RM-1) derived from the mouse prostate reconstitution (MPR) model syst