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An LC Method for the Determination of Bupropion and Its Main Metabolite, Hydroxybupropion in Human Plasma

✍ Scribed by Duygu Yeniceli; Dilek Dogrukol-Ak


Book ID
111791801
Publisher
Springer
Year
2009
Tongue
English
Weight
272 KB
Volume
70
Category
Article
ISSN
0009-5893

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## Abstract The anticancer drug capecitabine and its metabolites [including the active metabolite 5‐fluorouracil (5‐FU)] display high pharmacokinetic inter‐patient variability. Such variability, which may lead to treatment failure or toxicity, could need drug concentration measurement to individual