AN ITERATIVE CONVECTIVE-DIFFUSIVE MODEL OF DRUG TRANSPORT AND BINDING IN THE ARTERY WALL

An in vitro study of the influence of a

An in vitro study of the influence of a drug's molecular weight on its overall (Clt), diffusive (Cld) and convective (Clc) clearance through dialysers

✍ Dr. M. Valera Mac-Kay; I. Perez Fernandez; J. Herrera Carranza; J. Sanchez Burso 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 644 KB

The dialyser clearance of a drug is the sum of two components: one diffusive, arising from the concentration gradient across the membrane, and the other convective, arising from the ultrafiltration of plasma water, produced by the increases in hydraulic pressure that the membrane undergoes. To demo