✦ LIBER ✦
An isotherm model describing concave-down scatchard curve for heterogeneous affinity adsorption
✍ Scribed by Shing-Yi Suen
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1997
- Tongue
- English
- Weight
- 382 KB
- Volume
- 70
- Category
- Article
- ISSN
- 0268-2575
No coin nor oath required. For personal study only.
✦ Synopsis
A new isotherm model, derived for a concave-down Scatchard curve, is presented to Ðt the experimental results for pepsin and chymosin adsorption to pepstatin A affinity membranes. The new model is converted into a kinetic expression and used for the Ðtting of association curves. The results from the new kinetic model show a better agreement with the experimental data than the Langmuir kinetic model. The new kinetic model is also used together with the affinity membrane model to predict the single-solute breakthrough curves, which performs well in matching the experimental curves.