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An isobolographic analysis of the hypnotic effects of combinations of dexmedetomidine with fentanyl or diazepam in rats

✍ Scribed by Gyöngyi Horváth; Margit Szikszay; György Rubicsek; György Benedek


Book ID
118345277
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
341 KB
Volume
50
Category
Article
ISSN
0024-3205

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Pipequaline (PK 8165) is a putative mixed agonist/antagonist at benzodiazepine receptors. The effects of pipequaline and diazepam on memory were assessed in 12 normal volunteers. Diazepam 10 mg or placebo was added to two doses of pipequaline, 50 and 150 mg, or to placebo in a double-blind crossover