An investigation of whether polymorphisms of cytochrome P4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a Chinese population

An investigation of whether polymorphism

An investigation of whether polymorphisms of cytochrome P4502E1 are genetic markers of susceptibility to alcoholic end-stage organ damage in a chinese population

✍ You-Chen Chao; Tong-Ho Young; Wei-Kuo Chang; Hung-Shang Tang; Chung-Te Hsu 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 621 KB

The human cytochrome P4502El gene (P4502E1), coding for an ethanol-inducible nitrosamine-metabolizing P-450, is involved in the metabolism of ethanol and many known carcinogens. Recently, restriction fragment length polymorphisms (RFLps) within the P4502E1 have been suggested as genetic markers of s