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An investigation of the in vivo hydrolysis and absorption of propylene glycol distearate

โœ Scribed by C.L. Long; B.R. Zeitlin; R. Thiessen Jr.

Book ID
118841913
Publisher
Elsevier Science
Year
1958
Tongue
English
Weight
709 KB
Volume
77
Category
Article
ISSN
0003-9861

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Effect of propylene glycol on ibuprofen
Effect of propylene glycol on ibuprofen absorption into human skin in vivo
โœ Christophe Herkenne; Aarti Naik; Yogeshvar N. Kalia; Jonathan Hadgraft; Richard ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 227 KB ๐Ÿ‘ 1 views

The objective was to assess the impact of propylene glycol (PG), a common cosolvent in topical formulations, on the penetration of ibuprofen into human skin in vivo. Drug uptake into the stratum corneum (SC), following application of saturated formulations containing from 0 to 100% v/v PG, was asses