An investigation of the compression rate dependence on the surface pressure-surface area isotherm for a dipalmitoyl phosphatidylcholine monolayer at the air/water interface

✍ Scribed by A. Jyoti; R.M. Prokop; J. Li; D. Vollhardt; D.Y. Kwok; R. Miller; H. Möhwald; A.W. Neumann

• Publisher: Elsevier Science
• Year: 1996
• Tongue: English
• Weight: 564 KB
• Volume: 116
• Category: Article
• ISSN: 0927-7757
• DOI: 10.1016/0927-7757(96)03589-3

✦ Synopsis

In this study, the effects of the monolayer compression rate on the shape of the surface pressure-surface area (n-A) isotherm were investigated for dipalmitoyl phosphatidylcholine (DPPC) at the air/water interface. Both axisymmetric drop shape analysis and the Langmuir-Wilhelmy film balances were used for this study. It has recently been shown for octadecanol that a higher rate of compression shifts the lower part of the n-A isotherm to the right. However, the results of this DPPC study show no significant effect on the n-A isotherm shape for the range of compression rates used (1.60-371 ~2 per molecule per minute). The varied influence of the compression rates on different monolayers is explained by considering the molecular structure and the malleable nature of the domains, as well as the molecular pattern upon monolayer formation.