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An investigation of the biological effect of structural modifications of isothiosemicarbazones and their cyclic analogues

✍ Scribed by E Maccioni; M.C Cardia; S Distinto; L Bonsignore; A De Logu


Book ID
114019272
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
234 KB
Volume
58
Category
Article
ISSN
0014-827X

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## Abstract The toxic metabolite of the basidiomycete __Gloeophyllum abietinum__, oosponol (6b), and the structural analogues (Figure 1) were synthesised in order to investigate which partial structures of the molecules are responsible for their biological activities. Different organisms were emplo