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An Investigation into the Influence of Counterion on the Properties of Some Amorphous Organic Salts

✍ Scribed by Towler, Christopher S.; Li, Tonglei; Wikström, Håkan; Remick, David M.; Sanchez-Felix, Manuel V.; Taylor, Lynne S.


Book ID
120475382
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
627 KB
Volume
5
Category
Article
ISSN
1543-8384

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The effects of two contra-ions, namely benzoate (Bz) and oleate (Ol), on the in vitro human skin permeability of propranolol racemate (RS-PR) or S-enantiomer (S-PR) were studied. Saline solution (SS) or mineral oil (MO) were selected as vehicles. The MO increased the permeability coefficient (K(p))