An introduction to genetic engineering

✍ Scribed by Nicholl D.

• Publisher: CUP
• Year: 2010
• Tongue: English
• Leaves: 349
• Edition: draft, 3ed
• Category: Library

✦ Synopsis

In this third edition of his popular undergraduate-level textbook, Des Nicholl recognises that a sound grasp of basic principles is vital in any introduction to genetic engineering. Therefore, as well as being thoroughly updated, the book also retains its focus on the fundamental principles used in gene manipulation. The text is divided into three sections: Part I provides an introduction to the relevant basic molecular biology; Part II, the methods used to manipulate genes; and Part III, applications of the technology. There is a new chapter devoted to the emerging importance of bioinformatics as a distinct discipline. Other additional features include text boxes, which highlight important aspects of topics discussed, and chapter summaries, which include aims and learning outcomes. These, along with key word listings, concept maps and a glossary, will enable students to tailor their study to suit their own learning styles and ultimately gain a firm grasp of a subject that students traditionally find difficult.

✦ Table of Contents

Cover......Page 1
Abstract......Page 2
Title......Page 4
Copyright......Page 5
Contents......Page 6
Preface to the third edition......Page 12
1 Introduction......Page 15
Part I The basis of genetic engineering......Page 24
2 Introducing molecular biology......Page 25
3 Working with nucleic acids......Page 45
4 The tools of the trade......Page 63
Part II The methodology
of gene
manipulation......Page 74
5 Host cells and vectors......Page 75
6 Cloning strategies......Page 103
7 The polymerase chain reaction......Page 129
8 Selection, screening, and
analysis of recombinants......Page 145
9 Bioinformatics......Page 165
Part III
Genetic
engineering
in action......Page 182
10 Understanding genes,
genomes, and ‘otheromes’......Page 183
11 Genetic engineering
and biotechnology......Page 215
12 Medical and forensic
applications of gene
manipulation......Page 239
13
Transgenic plants and animals......Page 269
14 The other sort of cloning......Page 291
15
Brave new world or genetic
nightmare?......Page 304
Suggestions for further reading......Page 310
Using the World Wide Web......Page 312
Glossary......Page 316
Index......Page 340