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πŸ“

An Introduction to Computational Systems Biology: Systems-Level Modelling of Cellular Networks

✍ Scribed by Karthik Raman

Publisher
Chapman and Hall/CRC
Year
2021
Tongue
English
Leaves
359
Series
Chapman & Hall/CRC Computational Biology Series
Edition
1
Category
Library
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✦ Synopsis

This book delivers a comprehensive and insightful account of applying mathematical modelling approaches to very large biological systems and networks―a fundamental aspect of computational systems biology. The book covers key modelling paradigms in detail, while at the same time retaining a simplicity that will appeal to those from less quantitative fields.

✦ Table of Contents

Dedication
Contents
Preface
1. Introduction to modelling
Part I: Static Modelling
2. Introduction to graph theory
3. Structure of networks
4. Applications of network biology
Part II: Dynamic Modelling
5. Introduction to dynamic modelling
6. Parameter estimation
7. Discrete dynamic models: Boolean networks
Part III: Constraint-based Modelling
8. Introduction to constraint-based modelling
9. Extending constraint-based approaches
10. Perturbations to metabolic networks
Part IV: Advanced Topics
11. Modelling cellular interactions
12. Designing biological circuits
13. Robustness and evolvability of biological systems
14. Epilogue: The road ahead
Online-only appendices
Index

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