✦ LIBER ✦

An intramolecular, Ni(0)-mediated approach to the nonracemic biaryl portion of vancomycin

✍ Scribed by Bruce H. Lipshutz; Peter Müller; Dirk Leinweber

Book ID: 104261341
Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 195 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(99)00557-2

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✦ Synopsis

Using a tether derived from tartaric acid to which is attached two halogenated phenylglycine residues, a Ni(O)-induced biaryl coupling can be effected with complete control of axial chirality.

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