A novel D + BCD + ABCD route to ll-keto steroids is reported involving a high yield stereoselective intramolecular Diels-Alder reaction of furan-diene 5a in water as a key-step. The dienophilic side chain is readily introduced starting from 2 via a sequence involving alkylation with ethyl 4-iodo-3-
An Intramolecular Furan−Diene Diels−Alder Approach to 11-Oxo 10α-Steroids
✍ Scribed by Sandra Claeys; Dirk Van Haver; Pierre J. De Clercq; Marco Milanesio; Davide Viterbo
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 524 KB
- Volume
- 2002
- Category
- Article
- ISSN
- 1434-193X
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