𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An Intramolecular Furan−Diene Diels−Alder Approach to 11-Oxo 10α-Steroids

✍ Scribed by Sandra Claeys; Dirk Van Haver; Pierre J. De Clercq; Marco Milanesio; Davide Viterbo


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
524 KB
Volume
2002
Category
Article
ISSN
1434-193X

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Intramolecular diels-alder reaction with
✍ Luc A Van Royen; Roelant Mijngheer; Pierre J De Clercq 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 255 KB

A novel D + BCD + ABCD route to ll-keto steroids is reported involving a high yield stereoselective intramolecular Diels-Alder reaction of furan-diene 5a in water as a key-step. The dienophilic side chain is readily introduced starting from 2 via a sequence involving alkylation with ethyl 4-iodo-3-

Intramolecular diels-alder reaction with
✍ Luc A. Van Royen; Roelant Mijngheer; Pierre J. De Clercq 📂 Article 📅 1982 🏛 Elsevier Science 🌐 French ⚖ 238 KB

Depending on the reaction conditions the intramolecular Diels-Alder reaction of furan-diene 14 yields predominantly either one of two adducts 16a and 16b , which possess the necessary --functionality for eventual transformation into corticosteroids. The dienophile was intro-

A novel approach to periplanone-b involv
✍ Serge G. Cauwberghs; Pierre J. De Clercq 📂 Article 📅 1988 🏛 Elsevier Science 🌐 French ⚖ 289 KB

The 6-step sequence to trienone 2, a known intermediate for the total synthesis of periplanone-B, involves the conversion of 2 into 5 using dilithiated propadiene, the IMDA of 4 to E-adducts 1 and 6, the conversion of 2 to diol S via a radical anion promoted cleavage of the oxygen bridge, and a in-s

Intramolecular Diels-Alder Reaction with
✍ Luc A. van Royen; Roelant Mijngheer; Pierre J. De Clercq 📂 Article 📅 2010 🏛 Wiley (John Wiley & Sons) ⚖ 1012 KB

A novel Approach f o r t h e s y n t h e s i s of t h e BCD-ring system i n s t e r o i d s i s d e s c r i b e d . The sequence centers about t h e i n t r a m o l e c u l a r Diels-Alder r e a c t i o n of f u r a n 1 5 , which, depending on t h e r e a c t i o n c o n d i t i o n s , l e a d s pr