An intermolecular 1,3-dipolar cycloaddition approach to the tricyclic core of martinelline and martinellic acid
✍ Scribed by Miklós Nyerges; Imre Fejes; László Tőke
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 91 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The tricyclic core of the martinellines has been synthesised stereoselectively in two steps, using 1,3-dipolar cycloaddition of azomethine ylides as a key step.
📜 SIMILAR VOLUMES
An expedient method for the assembly of the pyrroloquinoline skeleton found in the martinelline alkaloids using a [3+2] cycloaddition of an azomethine ylide and an alkene has been developed.
The 1,3-dipolar cycloaddition of formaldehyde N-electrostatic interactions in the reaction TS. The force field approach previously developed for evaluating the benzylnitrone with βЈ-alkoxyand γ-alkoxy-α,β-unsaturated esters was investigated. The stereochemical outcome of stereoselection in nitrile o