Metabolic shifts do not influence the gl
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Helder J. Cruz; Cristina M. Peixoto; Manfred Nimtz; Paula M. Alves; Elsa M. Dias
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Article
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2000
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John Wiley and Sons
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English
โ 254 KB
๐ 1 views
BHK-21 cells expressing a human IgG-IL2 fusion protein, with potential application in tumor-targeted therapy, were grown under different nutrient conditions in a continuous system for a time period of 80 days. At very low-glucose (< 0.5 mM) or glutamine (< 0.2 mM) concentrations, a shift toward an e