An integrated microcomputer system to maintain a genetic register for Huntington disease

✍ Scribed by Sarfarazi, Mansoor ;Quarrell, Oliver W. J. ;Wolak, Geoffrey ;Harper, Peter S. ;Opitz, John M. ;Reynolds, James F.

• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: English
• Weight: 393 KB
• Volume: 28
• Category: Article
• ISSN: 0148-7299
• DOI: 10.1002/ajmg.1320280427

✦ Synopsis

A microcomputer program has been designed to maintain a large data base for Huntington disease. This program facilitates such data manipulation as adding, altering, retrieving, deleting, and printing pedigrees. The program is self-contained and has a risk-calculating routine built in which automatically provides both the Mendelian and age-modified risks. This package is capable of printing the pedigrees on a simple printer or, altematively, creates an output-file which can be used with a dedicated plotting program for drawing the pedigrees and their data on a plotter. The program has a routine which can provide a series of statistical data from the register including age-of-onset, diagnosis, death, and other useful information.