𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An Integrated Metabonomic Investigation of Acetaminophen Toxicity in the Mouse Using NMR Spectroscopy

✍ Scribed by Coen, Muireann; Lenz, Eva M.; Nicholson, Jeremy K.; Wilson, Ian D.; Pognan, Francois; Lindon, John C.


Book ID
124060086
Publisher
American Chemical Society
Year
2003
Tongue
English
Weight
179 KB
Volume
16
Category
Article
ISSN
0893-228X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Acute liver acetaminophen toxicity in ra
✍ Athina Zira; Emmanuel Mikros; Konstantina Giannioti; Panagiota Galanopoulou; Apo πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 636 KB

## Abstract The metabonomic approach has been widely used in toxicology to investigate mechanisms of toxicity. In the present study alterations in the metabolic profiles, monitored by ^1^H‐NMR spectroscopy, on serum samples in acetaminophen (APAP)‐induced liver injury in rabbits were examined. Furt

Investigation of the Metabolite Variatio
✍ A.Rosemary Tate; Stephen J.P. Damment; John C. Lindon πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 147 KB

An exploratory statistical analysis has been undertaken of 640 (1)H NMR spectra of rat urine, obtained from predose and control animals during the course of eight separate toxicology studies. The aim was to determine the degree and type of variation between (1)H NMR spectra from such control animals