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An Insight into the Mechanism of Inhibition and Reactivation of the F 1 -ATPases by Tentoxin †

✍ Scribed by Santolini, Jérôme; Minoletti, Claire; Gomis, Jean-Marie; Sigalat, Claude; André, François; Haraux, Francis

Book ID
126956060
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
287 KB
Volume
41
Category
Article
ISSN
0006-2960

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Evidence shows that Na(+)/K(+)-ATPase from kidney, brain and liver is inhibited by nitric oxide (NO) and peroxynitrite anion (ONO(2) (-)), but the mechanism is unknown. The aim of the present work was to study the inhibitory effect of NO and ONO(2) (-) on erythrocyte Na(+)/K(+)-ATPase. Erythrocyte m