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An initial comparative map of copy number variations in the goat (Capra hircus) genome

✍ Scribed by Luca Fontanesi; Pier Luigi Martelli; Francesca Beretti; Valentina Riggio; Stefania Dall'Olio; Michela Colombo; Rita Casadio; Vincenzo Russo; Baldassare Portolano

Book ID: 115003430
Publisher: BioMed Central
Year: 2010
Tongue: English
Weight: 847 KB
Volume: 11
Category: Article
ISSN: 1471-2164
DOI: 10.1186/1471-2164-11-639

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## Abstract We have undertaken an extensive high‐resolution analysis of loss of heterozygosity (LOH) in 30 high grade gliomas using the Affymetrix 100K SNP mapping array. Only 70% of LOH events were accompanied by a copy number loss (CNA~loss~), and of the other 30%, the distal region of 17p prefer