✦ LIBER ✦

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

✍ Scribed by Soucy, Teresa A.; Smith, Peter G.; Milhollen, Michael A.; Berger, Allison J.; Gavin, James M.; Adhikari, Sharmila; Brownell, James E.; Burke, Kristine E.; Cardin, David P.; Critchley, Stephen

Book ID: 109898095
Publisher: Nature Publishing Group
Year: 2009
Tongue: English
Weight: 528 KB
Volume: 458
Category: Article
ISSN: 0028-0836
DOI: 10.1038/nature07884

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Self-renaturing enzymes: Design of an en

Self-renaturing enzymes: Design of an enzyme-chaperone chimera as a new approach to enzyme stabilization

✍ Lisa M. Bergeron; Lizabeth Gomez; Timothy A. Whitehead; Douglas S. Clark 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 221 KB 👁 1 views

## Abstract Molecular chaperones in aqueous‐organic mixtures can broaden the utility of biocatalysis by stabilizing enzymes in denaturing conditions. We have designed a self‐renaturing enzyme‐chaperone chimera consisting of penicillin amidase and a thermophilic chaperonin that functions in aqueous‐

Activation of mGlu2/3 receptors as a new

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

✍ Patil, Sandeep T; Zhang, Lu; Martenyi, Ferenc; Lowe, Stephen L; Jackson, Kimberl 📂 Article 📅 2007 🏛 Nature Publishing Group 🌐 English ⚖ 234 KB

Corrigenda: Activation of mGlu2/3 recept

Corrigenda: Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

✍ Andreev, Boris V; Avedisova, Alla S; Bardenstein, Leonid M; Gurovich, Issak Y; M 📂 Article 📅 2007 🏛 Nature Publishing Group 🌐 English ⚖ 47 KB

ChemInform Abstract: An Easy Approach to

ChemInform Abstract: An Easy Approach to the Synthesis of Optically Active vic-Diols: A New Single-Enzyme System.

✍ O. BORTOLINI; G. FANTIN; M. FOGAGNOLO; P. P. GIOVANNINI; A. GUERRINI; A. MEDICI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

Inhibition of oncogene product enzyme ac

Inhibition of oncogene product enzyme activity as an approach to cancer chemoprevention. Tyrosine-specific protein kinase inhibition by daphnoretin from Thymelaea hirsuta root

✍ Mohamed Abou-Karam; Nagwa S. El-Shaer; W. Thomas Shier 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 91 KB 👁 2 views

Inhibitors of oncogene product enzyme activity were sought as a prescreen for potential cancer chemopreventive agents. Daphnoretin, a dicoumaryl ether from Thymelaea hirsuta root, inhibited the erb-b oncogene product, the tyrosine-specific protein kinase of human epidermal growth factor receptor (IC

Inhibition of oncogene product enzyme ac

Inhibition of oncogene product enzyme activity as an approach to cancer chemoprevention. Tyrosine-specific protein kinase inhibition by purpurogallin from Quercus sp. Nutgall

✍ Mohamed Abou-Karam; Dr. W. Thomas Shier 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 56 KB 👁 2 views

Inhibitors of oncogene product enzyme activity were sought as a prescreen for potential cancer chemopreventive agents. Purpurogallin, a polyphenol from Quercus sp. nutgall, was found to inhibit the tyrosine-specific protein kinase of the human erb-b oncogene product (epidermal growth factor receptor