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An Information Theoretic Approach to Macromolecular Modeling: I. Sequence Alignments

โœ Scribed by Aynechi, Tiba; Kuntz, Irwin D.


Book ID
119919163
Publisher
Biophysical Society
Year
2005
Tongue
English
Weight
224 KB
Volume
89
Category
Article
ISSN
0006-3495

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An iterative structure-assisted approach
โœ David F. Burke; Charlotte M. Deane; Hampapathalu A. Nagarajaram; Nuria Campillo; ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 267 KB ๐Ÿ‘ 2 views

Correct alignment of the sequence of a target protein with those of homologues of known three-dimensional structure is a key step in comparative modeling. Usually an iterative approach that takes account of the local and overall structural features is required. We describe such an approach that expl