## Abstract An informationβtheoretical approach, which combines a sequence decomposition technique and a fuzzy clustering algorithm, is proposed for prediction of protein structural class. This approach could bypass the process of selecting and comparing sequence features as done previously. First,
An information theoretic approach for improving data driven prediction of protein model quality
β Scribed by Alfonso Montuori; Giovanni Raimondo; Eros Pasero
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 778 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0898-1221
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β¦ Synopsis
We present the results of an information theory-based approach to select an optimal subset of features for the prediction of protein model quality. The optimal subset of features was calculated by means of a backward selection procedure. The performances of a probabilistic classifier modeled by means of a Kernel Probability Density Estimation method (KPDE) were compared with those of a feed-forward Artificial Neural Network (ANN) and a Support Vector Machine (SVM).
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