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An indolent penile herpetic ulcer in a patient with previously undiagnosed human immunodeficiency virus infection

✍ Scribed by Tayal; Pattman; Mclelland; Sviland; Snow

Book ID
104458617
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
391 KB
Volume
138
Category
Article
ISSN
0007-0963

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✦ Synopsis

We report a case of an atypical penile herpetic ulcer in a man with previously undiagnosed human immunodeficiency virus (HIV) infection. Swabs of the lesion were negative for herpes simplex virus (HSV) by culture and electron microscopy. However, histopathology of biopsy material showed characteristic herpetic multinucleate giant cells. Immunochemistry using polyclonal antibodies was positive for HSV1 and HSV2. The lesion completely resolved after treatment with aciclovir and the patient subsequently tested positively for HIV antibodies.

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