An indium mediated efficient chemoselective deoxygenation of N-oxides and nitrones
β Scribed by Md Ilias; Dhiren C Barman; Dipak Prajapati; Jagir S Sandhu
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- French
- Weight
- 62 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
A simple and inexpensive procedure for the deoxygenation of N-oxides, such as N-arylnitrones, azoxybenzenes and N-heteroarene N-oxides with indium trichloride in acetonitrile at ambient pressure is described. The procedure gives high yields of deoxygenated products.
π SIMILAR VOLUMES
Several aromatic and aliphatic amine-N-oxides were deoxygenated to the corresponding amines in good to quantitative yield using indium metal in neutral aqueous media. Other functional groups such as alkenes, halides, esters, ethers, nitriles, amides and sulfones are unaffected under the present reac
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