An increase of collagen biosynthesis in livers of rats submitted to chronic intoxication with ethanol

✍ Scribed by Edward Bańkowski; Elźbieta Pawlicka

• Book ID: 104670679
• Publisher: Springer
• Year: 1989
• Tongue: English
• Weight: 394 KB
• Volume: 85
• Category: Article
• ISSN: 0300-8177
• DOI: 10.1007/bf00223512

✦ Synopsis

It was found that chronic intoxication of rats with ethanol results in a distinct, progressive increase of 5(3)H-proline incorporation into collagen synthesized by liver. At the same time biosynthesis of other proline-containing proteins in rat liver slightly decreases. These effects precede the morphological symptoms of liver damage induced by ethanol.