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An in vitro pharmacological model of vascular smooth muscle

โœ Scribed by Tahir Hussain; S.Jamal Mustafa


Book ID
113409788
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
559 KB
Volume
30
Category
Article
ISSN
1056-8719

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Relaxant effects of mefloquine on vascul
โœ B. J. Adegunloye; O. A. Sofola; H. A. B. Coker ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› Springer ๐ŸŒ English โš– 345 KB

We have studied the effects of mefloquine on isolated rat aorta. Mefloquine (10(-8) to 1.6 x 10(-4) mol.l-1) relaxed aortic rings precontracted with both noradrenaline (10(-7) mol.l-1) and potassium chloride (60 mmol.l-1). The mefloquine-induced relaxation was somewhat attenuated by removal of the e