An in vitro model to study cellular photosensitizer uptake and photodynamic dose-response relationships of tumor cells

The relationship between tumour geometry

The relationship between tumour geometry and the response of tumour cells to cytotoxic drugs — An in vitro study using EMT6 multicellular spheroids

✍ T. T. Kwok; P. R. Twentyman 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 746 KB

## Abstract Multicellular spheroids of the EMT6/Ca/VJAC mouse mammary tumour cell line have been used in an investigation of the effect of tumour geometry on the response of tumour cells to 3 cytotoxic drugs, adriamycin (ADM), nitrogen mustard (HN2) and CCNU. In addition to the inherent cellular dr