An In Vitro Investigation of the Relationships Between Potency, Lipophilicity, Cytotoxicity and Chemical Class of Representative Calcium Antagonist Drugs

The relationship between tumour geometry

The relationship between tumour geometry and the response of tumour cells to cytotoxic drugs — An in vitro study using EMT6 multicellular spheroids

✍ T. T. Kwok; P. R. Twentyman 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 French ⚖ 746 KB

## Abstract Multicellular spheroids of the EMT6/Ca/VJAC mouse mammary tumour cell line have been used in an investigation of the effect of tumour geometry on the response of tumour cells to 3 cytotoxic drugs, adriamycin (ADM), nitrogen mustard (HN2) and CCNU. In addition to the inherent cellular dr