An Improved Synthesis of 1,2,4-Triazoline-3,5-diones
โ Scribed by Stickler, J. C.; Pirkle, W. H.
- Book ID
- 111953301
- Publisher
- American Chemical Society
- Year
- 1966
- Tongue
- English
- Weight
- 281 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
Vitamin A and its me&x&es reacted with 1,2,4-ttiazoline-3,Mione.s to give 11,14-(retinal) or 7, IO-adduct (retinal and retinoic acid) with high regioselectkity depending on the nature of the terminal functional group. The regiosekctivity of the reaction was discussed in compared with that with singl
## Abstract The reaction of 2(1__H__)โpyrazinones 1 and 1,2,4โtriazolineโ3,5โdiones 3 was investigated by comparing that of 1 with singlet oxygen. 2(1__H__)โPyrazinones 1 reacted in DielsโAlder fashion with 1,2,4โtriazolineโ3,5โdiones 3 to afford [4+2]โadducts 4โ17 in high yields.
DIENOPHILIC reactivity rises in the series fumaric acid, maleic acid, maleic anhydride' and the well recognized dienophilic properties of azodicarboxylic ester2 place it last in this series ahead of maleic anhydride. However, it fails to react (or reacts by allylic addition) with some dienes with wh