✦ LIBER ✦

An improved process for the synthesis of DMTMM-based coupling reagents

✍ Scribed by Steven A. Raw

Book ID: 108285347
Publisher: Elsevier Science
Year: 2009
Tongue: French
Weight: 292 KB
Volume: 50
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2008.12.047

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

An improved coupling procedure for the b

An improved coupling procedure for the barton-zard pyrrole synthesis

✍ Pavel Bobál; David A. Lightner 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 38 KB

## Abstract An improved final step in the Barton‐Zard pyrrole synthesis uses inexpensive potassium carbonate as base in the coupling‐cyclization reaction of __vic__‐nitro‐acetates with isocyanides. In this modification the isolated yields of synthetically useful 2‐carboalkoxypyrroles (**1a,b** and

Improved procedure for the synthesis of

Improved procedure for the synthesis of thiazolium-type peptide coupling reagents: BMTB as a new efficient reagent

✍ Ralf Wischnat; Joachim Rudolph; Roman Hanke; Roger Kaese; Achim May; Heidi Theis 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 108 KB

An efficient scalable synthesis of 2-halothiazolium-type peptide coupling reagents has been developed. The key step is the formation of the 2-bromothiazole scaffold through cyclization of a-thiocyanato ketones with hydrogen bromide. Using this method, the new coupling reagent 2-bromo-N-methylthiazol

Improved Procedure for the Synthesis of

Improved Procedure for the Synthesis of Thiazolium-Type Peptide Coupling Reagents: BMTB as a New Efficient Reagent.

✍ Ralf Wischnat; Joachim Rudolph; Roman Hanke; Roger Kaese; Achim May; Heidi Theis 📂 Article 📅 2003 🏛 John Wiley and Sons ⚖ 85 KB 👁 1 views

An Improved Sulfurization Reagent for th

An Improved Sulfurization Reagent for the Synthesis of Sulfur-Containing Oligonucleotides

✍ SERGE L. BEAUCAGE; RADHAKRISHNAN P. IYER; WILLIAM EGAN; JUDITH B. REGAN 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB

An improved synthesis and selective coup

An improved synthesis and selective coupling of a hydroxy based photolabile linker for solid phase organic synthesis

✍ Darren L. Whitehouse; Sergey N. Savinov; David J. Austin 📂 Article 📅 1997 🏛 Elsevier Science 🌐 French ⚖ 113 KB

Addition of HOAt dramatically improves t

Addition of HOAt dramatically improves the effectiveness of pentafluorophenyl-based coupling reagents

✍ J. Klose; A. El-Faham; P. Henklein; L.A. Carpino; M. Bienert 📂 Article 📅 1999 🏛 Elsevier Science 🌐 French ⚖ 209 KB

In the course of comparing the effectiveness of several HOAt-and HOPfp-derived coupling reagents by cyclization and segment condensation of model sequences, using HPLC to follow the time course and to determine the outcome in terms of oligomerization and epimerization, we found a striking improvemen