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An improved procedure for the synthesis of vinylphosphonate-linked nucleic acids

✍ Scribed by Sahar Abbas; Christopher J Hayes

Book ID
108379794
Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
128 KB
Volume
41
Category
Article
ISSN
0040-4039

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An improved procedure for the preparation and purification of labeled fatty acids by malonic ester synthesis has been developed. This method uses the different hydrolysis rates of the monoalkylmalonic ester intermediate and its dialkylmalonic ester side product. A convenient GC-MS monitoring techniq