𝔖 Bobbio Scriptorium
✦   LIBER   ✦

An improved one-pot method for the stereoselective synthesis of the (2S,3R)-3-amino-2-hydroxy acids: key intermediates for bestatin and amastatin

✍ Scribed by Herranz, Rosario; Castro-Pichel, Julia; Vinuesa, Soledad; Garcia-Lopez, M. Teresa


Book ID
115484646
Publisher
American Chemical Society
Year
1990
Tongue
English
Weight
421 KB
Volume
55
Category
Article
ISSN
0022-3263

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


A novel synthesis of the (2R,3S)- and (2
✍ Yuko Kobayashi; Yoshiji Takemoto; Yoshio Ito; Shiro Terashima πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier Science 🌐 French βš– 317 KB

The title synthesis could be accomplished by featuring the [2+21-cycloaddition reaction of a chiral imine with benzyloxyketene, alcoholysis of the formed 2-azetidinone derivative, and reductive removal of the mandelate-derived benzylic oxygen by way of a 2-oxazolidone derivative. Optically active 3