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An improved method for chromosome banding after fluorescencein situhybridization: Use of a tetramethylrodhamine-conjugated BrdU antibody

✍ Scribed by Albertina Sario; Luigi Carli; Elena Raimondi


Book ID
104635935
Publisher
Springer
Year
1991
Tongue
English
Weight
557 KB
Volume
7
Category
Article
ISSN
0920-9069

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✦ Synopsis


A method for high quality chromosome banding after in situ hybridization with biotinylated probes has been developed. Fluoresceine-conjugated avidin is used for probe detection, while chromosome banding is performed with a tetramethylrodhamine-conjugated anti-BrdU antibody. In this way probe localization and chromosome identification can be performed simultaneously simply by changing the incidental light wavelength.