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An improved HPLC system for the analysis and purification of organic amine radiopharmaceuticals

✍ Scribed by M.J. Adam; J.R. Grierson; S. Jivan

Publisher
Elsevier Science
Year
1989
Weight
146 KB
Volume
40
Category
Article
ISSN
0883-2889

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✦ Synopsis

This paper describes the separation of lipophilic amine radiopharmaceuticals on normal phase silica using a reversed phase type eluant. This class of compound usually gives very poor peak symmetry on reversed phase columns. However, excellent separation of a number of amines of interest to Positron Emission Tomography, such as spiperone and its derivatives, has been achieved on this system.

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