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An improved DEPT–HMQC sequence for high-throughput NMR analysis

✍ Scribed by Timothy Spitzer; Andrea M. Sefler; Randy Rutkowske

Book ID
102527046
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
177 KB
Volume
39
Category
Article
ISSN
0749-1581

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✦ Synopsis

Abstract

Two new pulse sequences are presented for the acquisition of DEPT–HMQC spectra, based on the original experiment of Kessler et al. The new sequences employ modifications intended to make the experiment well suited for high‐throughput acquisition and automated analysis. The sequences use coherence selection with gradients to reduce artifacts and constant‐time evolution to suppress unwanted F~1~ modulation. In addition, the new sequences require fewer pulses than the original experiment, and perform well even when pulse lengths are slightly mis‐set. Copyright © 2001 John Wiley & Sons, Ltd.

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