𝔖 Bobbio Scriptorium
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An Immunoelectrophoretic analysis of antigens reacting with lupus serum

✍ Scribed by William A. Atchley

Book ID
102749756
Publisher
John Wiley and Sons
Year
1961
Tongue
English
Weight
537 KB
Volume
4
Category
Article
ISSN
0004-3591

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✦ Synopsis

Abstract

The serum of patients with systemic lupus erythematosus may contain antibodies reacting in a variety of ways against several intracellular antigens. This report describes a new method of analyzing these antigen‐antibody reactions by immunoelectrophoresis on cellulose acetate membranes. The results show that abnormal sera may contain at least two different precipitating antibodies, one directed against a deoxy‐ribonucleohistone complex, and the other directed against an antigen that may be histone not attached to DNA.

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