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An Iminodiacetic Acid Based Lanthanide Binding Tag for Paramagnetic Exchange NMR Spectroscopy

✍ Scribed by Dr. James D. Swarbrick; Phuc Ung; Sandeep Chhabra; Dr. Bim Graham

Publisher: John Wiley and Sons
Year: 2011
Tongue: English
Weight: 485 KB
Volume: 50
Category: Article
ISSN: 0044-8249
DOI: 10.1002/anie.201007221

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## Abstract Paramagnetic effects from lanthanide ions present powerful tools for protein studies by nuclear magnetic resonance (NMR) spectroscopy provided that the lanthanide can be site‐specifically and rigidly attached to the protein. A new, particularly small and rigid lanthanide‐binding tag, 3‐