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An Extracellular Domain of BK Channel β1 Accessory Subunit Modulates the Activities of Voltage Sensor and Gate

✍ Scribed by Gruslova, Aleksandra; Semenov, Iurii; Wang, Bin

Book ID
122261923
Publisher
Biophysical Society
Year
2012
Tongue
English
Weight
41 KB
Volume
102
Category
Article
ISSN
0006-3495

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Voltage-gated calcium channels (Ca(V)s) govern muscle contraction, hormone and neurotransmitter release, neuronal migration, activation of calcium-dependent signalling cascades, and synaptic input integration. An essential Ca(V) intracellular protein, the beta-subunit (Ca(V)beta), binds a conserved