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An exploratory study on STX6, MOBP, MAPT, and EIF2AK3 and late-onset Alzheimer's disease

โœ Scribed by Liu, Qiu-Yan; Yu, Jin-Tai; Miao, Dan; Ma, Xiao-Ying; Wang, Hui-Fu; Wang, Wei; Tan, Lan


Book ID
123358440
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
153 KB
Volume
34
Category
Article
ISSN
0197-4580

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## Abstract The __MAPT__ gene that encodes Tau is located on chromosome 17q21, in a region, which has evolved to form two major haplotypes, H1 and H2. There is strong evidence that the H1 haplotype, and a subโ€haplotype (H1C), are overrepresented and associated with increased risk for the sporadic t