An Explorative Investigation into the Reaction of Ammonia with Ketones. Mediated by Low-Valent Titanium

✍ Scribed by E. Volckaerts; H. J. Geise; F. Daelemans

• Publisher: Wiley (John Wiley & Sons)
• Year: 2010
• Weight: 316 KB
• Volume: 101
• Category: Article
• ISSN: 0037-9646
• DOI: 10.1002/bscb.19921010610

✦ Synopsis

Mediated by low-valent titanium. generated from TiC13ILiA14. ammonia is incorporated into benzophenone to give N-(diphenylmethy1ene)-N-ldiphenylmethyl) amine in a synthetically useful reaction. A good yield 165 % ) requires that the temperatures of the reaction stages are well controled and that ammonia and ketone are simultaneously introduced keeping their molar ration 1 : l .