An experimental study of the variability in the properties and quality of wet granules
โ Scribed by J.S. Fu; Y.S. Cheong; G.K. Reynolds; M.J. Adams; A.D. Salman; M.J. Hounslow
- Book ID
- 113860849
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 365 KB
- Volume
- 140
- Category
- Article
- ISSN
- 0032-5910
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๐ SIMILAR VOLUMES
The objective is to provide mechanistic understanding of a preferred wet granulation process that a binder is added in a dry state. Blends of CaCO(3) and binders were prepared and used as model systems, and they were exposed to either 96% RH (rubbery/solution state) or 60% RH (glassy state) at room
The purpose of this study was to evaluate the influences of intrinsic drug mechanical properties and different granulation binder delivery processes on the physical and mechanical properties of high drug load granulations after wet granulation. Formulations (80% w/w) of acetaminophen (APAP), metform