An experimental study of hypothalamic connections in the guinea pig

✍ Scribed by Ferdinando Morin

• Publisher: John Wiley and Sons
• Year: 1950
• Tongue: English
• Weight: 980 KB
• Volume: 92
• Category: Article
• ISSN: 0021-9967
• DOI: 10.1002/cne.900920206

✦ Synopsis

Although numerous contributions have been made to the knowledge of the fiber coiinections of the hypothalamus, significant sources a i d terminations remain obscure, or in debate. A preliminary survey of the basal forebrain relations of the guinea pig suggested this animal as advantageous for a detailed investigation of points that remain under discussion, using small lesions and Narchi degeneration. The Marchi method does not allow any appreciation of the nonmyelinated componeiits of the hypothalamic systems, which are obvious with silver methods. Thus the observations reported are of positive character and do not negate the existence of non-myelinated connectioiis which may have provided the basis for the more extensive terminal distributions noted by other authors.

Sources in the literature used for orientation were the reviews of Ingrani ('40) and Brodal ('47), the studies of Gurdjian ('25, '27) and Krieg ('32) on the normal hypothalamus of the rat and of Young ('36) on the olfactory centers of the rabbit. Detailed comparison of my results with those of others is reserved for the discussion.

METHOD

Twelve guinea pigs, each of 400 gin weight, were used. Under anesthesia lesions were made with a sewing needle,