An experimental design for judging synergism on consideration to endocrine disruptor animal experiments

A statistical method for judging synergi

A statistical method for judging synergism: application to an endocrine disruptor animal experiment

✍ Nobuhito Matsunaga; Jun Kanno; Isao Yoshimura 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 79 KB

## Abstract This article proposes a statistical method for judging whether or not the combined action of chemicals is synergistic, being focused on the case in which two or more endocrine disruptors are made to act simultaneously. After defining synergism, the synergistic relation of two chemicals