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An expeditious synthesis of 1,2,3,4-tetrahydro-1,1-dimethylphenanthrenes

✍ Scribed by Ghosh, Sukumar; Banik, Bimal K.; Ghatak, Usha Ranjan


Book ID
121283459
Publisher
Royal Society of Chemistry
Year
1991
Weight
439 KB
Volume
12
Category
Article
ISSN
1472-7781

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## Abstract A convenient synthesis of 1‐(1,2,3,6‐tetrahydro‐1‐methyl‐4‐pyridinyl)ethanone, isoarecolone, starting with 4‐acetylpyridine is presented. 4‐Acetylpyridine was protected as the ketal followed by reaction with iodomethane to give the quaterary salt. The quaterary salt was reduced with sod